Journal: Juntendo Medical Journal
Article Title: The Role of Tumor-associated Macrophages in Colorectal Peritoneal Metastasis in Mice
doi: 10.14789/ejmj.JMJ24-0049-OA
Figure Lengend Snippet: (A) Protocol for macrophage inhibitor (clodronate) and an IL-10 inhibitor (AS101) injection into NOD SCID mice. (B) Macroscopic views and the mean weight of the peritoneal dissemination nodules from animals injected with clodronate and negative controls. The administration of clodronate significantly reduced the size of peritoneally disseminated nodules (P < 0.001). (C) Macroscopic views and the mean weight of the peritoneally disseminated nodules from animals injected with AS101 and negative controls.
Article Snippet: An IL-10 inhibitor AS101 (Tocris Bioscience, Bristol, UK) was injected (20 mg/mouse) on days 1-35 (control group: 4 mice, AS101 group: 3 mice).
Techniques: Injection